Keyword Analysis & Research: what type of mutation is missense


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Which of the following changes represents a missense mutation?

POINT MUTATION (one base is substituted for another) If a point mutation changes the amino acid, it’s called a MISSENSE mutation. If a point mutation does not change the amino acid, it’s called a SILENT mutation. If a point mutation changes the amino acid to a “stop,” it’s called a NONSENSE mutation.

What does nonsense mutation mean?

Nonsense Mutation Definition 1. A point mutation occurring within the protein-coding region of a gene, and which codes for a stop that can truncate the protein. (NCI Thesaurus) Definition 2. A mutation that alters the genetic code in a way that causes the premature termination of a protein.


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