Keyword Analysis & Research: plasma metanephrines

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Frequently Asked Questions

What causes elevated metanephrines?

Stress, illness strenuous physical activity, or withdrawal from opioids, benzodiazepines, alcohol or smoking may markedly increase metanephrines. Drugs that increase endogenous catecholamine levels can produce elevations of plasma metanephrines.

What does high metanephrines mean?

High values. High levels of free catecholamines, vanillylmandelic acid (VMA), or metanephrine can mean an adrenal gland tumor or other type of tumor is present. Any major stress, such as burns, a whole-body infection (sepsis), illness, surgery, or traumatic injury, can cause high levels.

What does a low metanephrine mean?

The catecholamines and metanephrines are usually measured together. Your overall pattern is low metanephrines. The reason that your physician was not concerned is that the primary reason for checking these tests is concern that they may be elevated, which is due to a hormone secreting tumor called a pheochromocytoma.

What is metanephrines test for?

The plasma free metanephrines test is used to help diagnose or rule out the presence of a rare tumor called a pheochromocytoma or a paraganglioma (PPGL) that releases excess metanephrines. Testing also may be used when a tumor has been treated or removed to monitor for recurrence.

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