Entresto Dosage Guide - Drugs.com
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Overview2.1 General Considerations2.2 Adult Heart Failure2.3 Pediatric Heart Failure2.4 Preparation of Oral Suspension2.5 Dose Adjustment for Patients Not Taking an ACE inhibitor or ARB or Previously Taking Low Doses of These Agents2.6 Dose Adjustment for Severe Renal Impairment2.7 Dose Adjustment for Hepatic ImpairmentFrequently asked questionsMore about Entresto (sacubitril / valsartan) In adults and pediatric patients with moderate hepatic impairment (Child-Pugh B classification), …Note: Initiate pediatric patients weighing 40 to 50 kg who meet this criterion at 0.8 mg/kg twice daily using the oral suspension [see Dosage and Administration (2.3, 2.4)]. No starting dose adjustment is needed for mild hepatic impairment.Use in patients with severe hepatic impairment is not recommended.
In adults and pediatric patients with moderate hepatic impairment (Child-Pugh B classification), …Note: Initiate pediatric patients weighing 40 to 50 kg who meet this criterion at 0.8 mg/kg twice daily using the oral suspension [see Dosage and Administration (2.3, 2.4)].
No starting dose adjustment is needed for mild hepatic impairment.Use in patients with severe hepatic impairment is not recommended.
DA: 16 PA: 54 MOZ Rank: 54
