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What is the definition of a neutral mutation?

In genetics, a neutral mutation is a mutation that has no effect on fitness. In other words, it is neutral with respect to natural selection. For example, some mutations in a DNA triplet or codon do not change which amino acid is introduced: this is known as a synonymous substitution.

Why are most mutations neutral?

Why are most mutations neutral in nature? The neutral theory of molecular evolution by Kimura in 1968 states that most evolutionary changes at the molecular level are caused by random genetic drift of selectively neutral nucleotide substitutions. Due to the degeneracy of the genetic code, some point mutations are silent with no amino acid ...

What is an example of a beneficial mutation?

There are several well-known examples of beneficial mutations. Here are two such examples: Mutations have occurred in bacteria that allow the bacteria to survive in the presence of antibiotic drugs, leading to the evolution of antibiotic-resistant strains of bacteria.


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