synonymous mutation | Synonymous vs. Nonsynonymous Mutations

Keyword	CPC	PCC	Volume	Score	Length of keyword
synonymous mutation	0.1	0.1	9591	97	19
synonymous	0.34	0.2	597	6	10
mutation	0.56	0.9	4008	20	8

Keyword	CPC	PCC	Volume	Score
synonymous mutation	0.29	0.9	619	89
synonymous mutation definition	1.64	0.1	5349	68
synonymous mutation examples	1.95	0.5	1451	30
synonymous mutation vs silent	1.16	0.5	9766	90
synonymous mutation vs silent mutation	0.56	0.5	5583	16
synonymous mutation vs nonsynonymous	1.59	0.3	6626	91
synonymous mutation rate	0.37	1	7007	44
synonymous mutations in representative yeast	1.7	0.6	8358	93
non synonymous mutation	1.28	1	621	72
what is a synonymous mutation	1.39	1	4099	32
synonymous and nonsynonymous mutation	1.92	0.9	2349	42
synonymous mutation meaning	0.42	1	7093	10
synonymous vs non synonymous mutations	1.51	0.5	5836	15
nonsynonymous vs synonymous mutations	1.97	0.1	4122	84

Search Results related to synonymous mutation on Search Engine

Synonymous vs. Nonsynonymous Mutations - Definitions
thoughtco.com

https://www.thoughtco.com/synonymous-vs-nonsynonymous-mutations-1224600

WEBJul 1, 2019 · Synonymous mutations do not change anything and no changes are made. That means they have no real role in the evolution of species since the gene or protein is not changed in any way. Synonymous mutations are actually fairly common, but since they have no effect, then they are not noticed.

DA: 16 PA: 20 MOZ Rank: 35

Understanding the contribution of synonymous mutations to
nature.com

https://www.nature.com/articles/nrg3051

WEBAug 31, 2011 · Synonymous mutations — sometimes called 'silent' mutations — are now widely acknowledged to be able to cause changes in protein expression, conformation and function.

DA: 91 PA: 10 MOZ Rank: 35

Synonymous substitution - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Synonymous_substitution

WEBA synonymous substitution (often called a silent substitution though they are not always silent) is the evolutionary substitution of one base for another in an exon of a gene coding for a protein, such that the produced amino acid sequence is not modified.

DA: 49 PA: 48 MOZ Rank: 71

Effects of Synonymous Mutations beyond Codon Bias: The …
oup.com

https://academic.oup.com/gbe/article/13/9/evab141/6300525

WEBJun 16, 2021 · Introduction. Synonymous mutations do not alter the encoded amino acids but can still impact fitness via their effects on gene expression and protein structure. Evidence for these fitness effects now comes from a range of observational, comparative genomics, and experimental studies.

DA: 66 PA: 6 MOZ Rank: 8

Synonymous mutations in representative yeast genes are mostly …
nature.com

https://www.nature.com/articles/s41586-022-04823-w

WEBJun 8, 2022 · Nature - A survey of 8,341 mutations in 21 yeast genes shows that synonymous mutations are nearly as harmful as nonsynonymous mutations, in part because they both affect the mRNA level of...

DA: 97 PA: 85 MOZ Rank: 46

Molecular Mechanisms and the Significance of Synonymous Mutations …
mdpi.com

https://www.mdpi.com/2218-273X/14/1/132

WEBJan 20, 2024 · If it results in a synonymous codon, often by changing only the third nucleotide or, in some cases, only the first nucleotide, it is called a synonymous mutation (SM). The term SM is relative and depends on what gene is used as a reference.

DA: 83 PA: 85 MOZ Rank: 16

A pan-cancer analysis of synonymous mutations - Nature
nature.com

https://www.nature.com/articles/s41467-019-10489-2

WEBJun 12, 2019 · Synonymous mutations have been viewed as silent mutations, since they only affect the DNA and mRNA, but not the amino acid sequence of the resulting protein. Nonetheless, recent studies...

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Exposing synonymous mutations - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/24954581/

WEBA large repertoire of both experimental and bioinformatic methods has been developed to understand the effects of synonymous variants. Results from this body of work have provided global insights into how biological systems exploit the degeneracy of the genetic code to control gene expression, protein folding efficiency, and the coordinated ...

DA: 84 PA: 18 MOZ Rank: 91

Nonsynonymous, synonymous and nonsense mutations in …
biomedcentral.com

https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5572-x

WEBApr 16, 2019 · Nonsynonymous mutations change the protein sequences and are frequently subjected to natural selection. The same goes for nonsense mutations that introduce pre-mature stop codons into CDSs (coding sequences). Synonymous mutations, however, are intuitively thought to be functionally silent and evolutionarily …

DA: 37 PA: 69 MOZ Rank: 58

Synonymous mutations that regulate translation speed might play …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033552/

WEBApr 9, 2021 · We found that synonymous mutations that increase the codon optimality could significantly enhance the translational velocity, and are enriched in oncogenes. The synonymous mutations that decrease codon optimality slow down translation, and are enriched in tumor suppressor genes.

DA: 51 PA: 22 MOZ Rank: 40