Keyword Analysis & Research: sox9


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sox90.390.26729914

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Keyword CPC PCC Volume Score
sox91.240.9786545

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  • SOX9 - Wikipedia

    wikipedia.org

    https://en.wikipedia.org/wiki/SOX9

    WebSox9, also known as SRY-Box Transcription Factor 9, is an important gene is sex determination. The SOX family of genes are all transcription factors for the Y chromosomal sex-determining factor SRY. The SRY gene encodes the SOX transcription factor while it upregulates Sox9.

    DA: 52 PA: 64 MOZ Rank: 29

  • SOX9 in organogenesis: shared and unique transcriptional functions

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482574/

    WebSep 17, 2022 · The transcription factor SOX9 is essential for the development of multiple organs including bone, testis, heart, lung, pancreas, intestine and nervous system. Mutations in the human SOX9 gene led to campomelic dysplasia, a haploinsufficiency disorder with several skeletal malformations frequently accompanied by 46, XY sex …

    DA: 88 PA: 2 MOZ Rank: 89

  • SOX9 gene: MedlinePlus Genetics

    medlineplus.gov

    https://medlineplus.gov/genetics/gene/sox9/

    WebThe SOX9 gene provides instructions for making a protein that plays a critical role during embryonic development. The SOX9 protein is especially important for development of the skeleton and plays a key role in the determination of sex before birth. The SOX9 protein attaches (binds) to specific regions of DNA and regulates the activity of other ...

    DA: 67 PA: 83 MOZ Rank: 10

  • SOX9 in cartilage development and disease - PMC - National …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956855/

    WebSOX9 is expressed from the multipotent skeletal progenitor stage until chondrocyte hypertrophic differentiation (blue shading of boxes) and has been shown to be involved in chondrocyte lineage specification, differentiation, and survival. Repression of SOX9 is required for osteoblast differentiation from progenitor cells and terminal ...

    DA: 89 PA: 22 MOZ Rank: 76

  • The pioneer factor SOX9 competes for epigenetic factors to

    nature.com

    https://www.nature.com/articles/s41556-023-01184-y

    WebJul 24, 2023 · The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates. Yihao Yang, Nicholas Gomez, Nicole Infarinato, Rene C. Adam, Megan Sribour, Inwha Baek, Mélanie Laurin & Elaine...

    DA: 12 PA: 94 MOZ Rank: 45

  • SOX9 Gene - GeneCards | SOX9 Protein | SOX9 Antibody

    genecards.org

    https://www.genecards.org/cgi-bin/carddisp.pl?gene=SOX9

    WebApr 3, 2024 · SOX9 (SRY-Box Transcription Factor 9) is a Protein Coding gene. Diseases associated with SOX9 include Campomelic Dysplasia and 46,Xx Sex Reversal 2. Among its related pathways are Gene expression (Transcription) and Mammalian disorder of …

    DA: 69 PA: 47 MOZ Rank: 94

  • SOX9: The Master Regulator of Cell Fate in Breast Cancer

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048250/

    WebSOX9 overexpression is a frequent event in breast cancer (BC) subtypes. Of note, the molecular mechanisms and functional regulation underlying SOX9 upregulation during BC progression are still being uncovered. The focus of this review is to appraise recent advances regarding the involvement of SOX9 in BC pathogenesis.

    DA: 7 PA: 65 MOZ Rank: 51

  • SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult ... - PubMed

    nih.gov

    https://pubmed.ncbi.nlm.nih.gov/28336567/

    WebApr 26, 2017 · We show here that SOX9 is an astrocyte-specific nuclear marker in all major areas of the CNS outside of the neurogenic regions. Based on SOX9 immunolabeling, we document that astrocytes constitute a smaller fraction of total cell number than previously estimated in the normal adult mouse brain.

    DA: 80 PA: 80 MOZ Rank: 32

  • Role of Sox9 in BPD and its effects on the Wnt/β-catenin ... - Nature

    nature.com

    https://www.nature.com/articles/s41420-023-01795-2

    WebJan 11, 2024 · Sox9 has been shown to be an important repressor of the Wnt/β-catenin signaling pathway and plays an important regulatory role in various pathophysiological processes.

    DA: 87 PA: 99 MOZ Rank: 8

  • SOX9: An emerging driving factor from cancer progression to …

    nih.gov

    https://pubmed.ncbi.nlm.nih.gov/33524528/

    WebPMID: 33524528. DOI: 10.1016/j.bbcan.2021.188517. Abstract. Dysregulation of transcription factors is one of the common problems in the pathogenesis of human cancer. Among them, SOX9 is one of the critical transcription factors involved in …

    DA: 89 PA: 37 MOZ Rank: 24