riplet | Sign Up

Keyword	CPC	PCC	Volume	Score	Length of keyword
riplet	1.87	0.7	9984	42	6

Keyword	CPC	PCC	Volume	Score
riplet	0.49	0.2	6555	50
riplet download windows	0.52	0.3	1073	15
riplet coding	0.1	0.3	4676	99
ripley	1.1	0.3	2277	91
riplet c++	1.5	0.6	6072	11
tripletex	0.15	0.5	227	48
replit python	0.58	0.7	9196	56
ripley 2024 torrent	0.25	0.1	1252	69
riplet browser	0.35	0.8	86	93
ripley login	0.84	1	429	27
ripley tn	0.78	1	1573	61
ripley cast	1.54	0.9	3330	68

Search Results related to riplet on Search Engine

Sign Up - Replit
replit.com

https://replit.com/login?goto=%2F~

WEBBuild and deploy software collaboratively with the power of AI without spending a second on setup.

DA: 88 PA: 80 MOZ Rank: 86

Replit
replit.com

http://www.replit.com/

WEBA computer for every idea. With instant environments, you get access to a computer for every branch, idea, or feature. Fork existing projects, start new projects, and context-switch quickly. It takes only a few seconds to fork and run large codebases that work on everyone's machine. Focus on building, we'll handle the rest.

DA: 4 PA: 14 MOZ Rank: 21

The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I
nature.com

https://www.nature.com/articles/s41467-023-42982-0

WEBNov 11, 2023 · Nature Communications - Riplet conjugates K63-Ub chain to RIG-I in order to induce a robust antiviral response, but the mechanism of action remains unclear. Here, the authors show that Riplet...

DA: 71 PA: 73 MOZ Rank: 64

RIG-I-like receptors: their regulation and roles in RNA sensing
nature.com

https://www.nature.com/articles/s41577-020-0288-3

WEBMar 13, 2020 · Riplet, which is one of the E3 ligases mediating RIG-I K63-linked ubiquitylation, was recently shown to promote RIG-I signalling in a ubiquitylation-independent manner.

DA: 25 PA: 75 MOZ Rank: 42

Regulation of RIG-I-like receptor-mediated signaling: interaction …
nature.com

https://www.nature.com/articles/s41423-020-00602-7

WEBJan 18, 2021 · Riplet (also known as RNF135 and REUL) is another critical K63-linked E3 ligase for RIG-I. 210,211,212 Riplet conjugates ubiquitin on multiple Lys residues in the CARD and CTD of RIG-I.

DA: 20 PA: 69 MOZ Rank: 96

Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/31006531/

WEBMay 16, 2019 · We report here that RIPLET, an essential E3 ligase in antiviral immunity, promotes the antiviral signaling activity of the viral RNA receptor RIG-I through both Ub-dependent and -independent manners. RIPLET uses its dimeric structure and a bivalent binding mode to preferentially recognize and ubiquitinate RIG-I pre-oligomerized on dsRNA.

DA: 27 PA: 65 MOZ Rank: 95

The Ubiquitin Ligase Riplet Is Essential for RIG-I-Dependent Innate
cell.com

https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(10)00381-1

WEBDec 16, 2010 · Riplet Is Essential for Triggering the RIG-I Signaling Pathway. We further examined the role of Riplet in RIG-I-mediated signaling during RNA virus infection. In RIG-I-mediated signaling, induction of type I IFNs and proinflammatory cytokines requires the activation of transcription factor IRF3.

DA: 13 PA: 38 MOZ Rank: 25

Riplet/RNF135, a RING Finger Protein, Ubiquitinates RIG-I to …
jbc.org

https://www.jbc.org/article/S0021-9258(20)71095-1/fulltext

WEBDownload Full Issue. Riplet/RNF135, a RING Finger Protein, Ubiquitinates RIG-I to Promote Interferon-β Induction during the Early Phase of Viral Infection* Hiroyuki Oshiumi. Misako Matsumoto. Shigetsugu Hatakeyama. Tsukasa Seya. Show footnotes. Open Access DOI: https://doi.org/10.1074/jbc.M804259200.

DA: 17 PA: 61 MOZ Rank: 77

Riplet Binds the Zinc Finger Antiviral Protein (ZAP) and Augments …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400502/

WEBRiplet is an E3 ubiquitin ligase containing three domains, an N-terminal RING finger domain, a central coiled-coil domain, and a C-terminal P/SPRY domain. We show that Riplet interacts with ZAP via its P/SPRY domain and that the ubiquitin ligase activity of Riplet is not required to stimulate ZAP-mediated virus inhibition.

DA: 33 PA: 69 MOZ Rank: 8

A Distinct Role of Riplet-Mediated K63-Linked Polyubiquitination …
plos.org

https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003533

WEBAug 8, 2013 · This result emphasizes the vital role of Riplet-mediated release of RIG-I RD autorepression in antiviral responses. Our results establish that Riplet releases RIG-I RD autorepression and demonstrated the biological significance of this mechanism in human innate immune responses.

DA: 68 PA: 63 MOZ Rank: 96