oatp | Organo anion transporter family

Keyword	CPC	PCC	Volume	Score	Length of keyword
oatp	1.29	1	8226	100	4

Keyword	CPC	PCC	Volume	Score
oatp	0.87	1	3952	65
oatp1b1	0.92	0.3	1787	54
oatpp	1.32	0.4	773	25
oatp1b3	0.01	0.3	5999	50
oatp inhibitors	1.52	0.2	2204	75
oatp1a2	0.32	0.2	4477	94
oatp2b1	1.91	0.3	740	69
oatp transporter	1.41	0.1	5805	38
oatp1a1	0.07	0.9	7550	56
oatp1b2	0.28	0.9	1270	47
oatpp github	0.99	0.6	5171	22
paypal	0.18	0.5	4282	20
oatp1a4	0.4	0.5	7875	81
oatp1b1 inhibitors	0.25	0.3	2106	14
oatpap	0.1	1	324	46
oatpp c++	0.89	0.1	7924	36
oatpak	1.18	0.1	5098	91
oatpp post	1.61	0.1	6377	67
oatpp mysql	1.67	0.5	8129	10

Search Results related to oatp on Search Engine

Organo anion transporter family - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Organo_anion_transporter_family

WEBMembers of the Organo Anion Transporter (OAT) Family ( organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers.

DA: 10 PA: 65 MOZ Rank: 48

Organic Anion Transporting Polypeptides - PMC - National …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996503/

WEBAbstract. Organic anion transporting polypeptides or OATPs are central transporters in the disposition of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of endogenous substrates. The critical role of OATPs in drug disposition has spurred research both in academia and in the pharmaceutical industry.

DA: 97 PA: 3 MOZ Rank: 96

OATPs, OATs and OCTs: the organic anion and cation transporters …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372714/

WEBOATPs. Organic anion transporting polypeptides (OATPs in humans, Oatps in rodents) are multispecific transporters located in numerous epithelia throughout the body. They mediate the cellular uptake of a broad range of substrates, including bile acids, steroid conjugates and numerous xenobiotics.

DA: 16 PA: 69 MOZ Rank: 22

Overview of organic anion transporters and organic anion …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906560/

WEBDec 6, 2019 · Both organic anion transporters (OATs) and organic anion transporter polypeptides (OATPs) belong to the SLC family. OATs are classified in the SLC22A superfamily. SLC22 transporters have at least six subfamilies: OAT, OAT-like, OAT-related, organic cation transporter (OCT), organic cation/carnitine transporter (OCTN), and …

DA: 93 PA: 29 MOZ Rank: 1

Structure of human drug transporters OATP1B1 and OATP1B3
nature.com

https://www.nature.com/articles/s41467-023-41552-8

WEBSep 18, 2023 · The organic anion transporting polypeptides OATP1B1 and OATP1B3 are membrane proteins that mediate uptake of drugs into the liver for subsequent conjugation and biliary excretion, a key step in...

DA: 6 PA: 16 MOZ Rank: 74

Cryo-EM structures of human organic anion transporting …
nature.com

https://www.nature.com/articles/s41422-023-00870-8

WEBSep 6, 2023 · Members of the solute carrier organic anion transporting polypeptide (OATPs) family function as transporters for a large variety of amphipathic organic anions including endogenous...

DA: 2 PA: 60 MOZ Rank: 93

Organic Anion Transporting Polypeptide (OATP) transporter expression …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/30347208/

WEBThis review aims to provide a comprehensive up-to-date overview regarding the expression, localization and function of OATP transporters in the human intestine. Keywords: Absorption; Interaction; Intestinal; OATP; Transporter; Uptake.

DA: 55 PA: 42 MOZ Rank: 29

Organic Anion-Transporting Polypeptide - an overview
sciencedirect.com

https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/organic-anion-transporting-polypeptide

WEBOrganic Anion Transporting Polypeptides (OATPs, SLCOs) represent a family of important membrane transport proteins within the solute carrier (SLC) superfamily that mediate the sodium-independent transport of a diverse range of amphiphilic organic compounds [51–56].

DA: 95 PA: 57 MOZ Rank: 66

Impact of OATP transporters on pharmacokinetics - Wiley
wiley.com

https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2009.00430.x

WEBOct 14, 2009 · Organic anion transporting polypeptides (OATP) form a family of influx transporters expressed in various tissues important for pharmacokinetics. Of the 11 human OATP transporters, OATP1B1, OATP1B3 and OATP2B1 are expressed on the sinusoidal membrane of hepatocytes and can facilitate the liver uptake of their substrate drugs.

DA: 86 PA: 50 MOZ Rank: 88

Organic Anion Transporting Polypeptides: Emerging Roles in
nih.gov

https://pubmed.ncbi.nlm.nih.gov/30782852/

WEBThis review focuses on the emerging roles for selected OATPs in cancer pharmacology, including preclinical and clinical studies suggesting roles in chemotherapy disposition, the pharmacogenetics of OATPs in cancer therapy, and OATP overexpression in various tumor tissues with implications for OATPs as therapeutic targets.

DA: 70 PA: 53 MOZ Rank: 31