methotrexate moa | Methotrexate - StatPearls

Keyword	CPC	PCC	Volume	Score	Length of keyword
methotrexate moa	1.73	0.7	8518	45	16
methotrexate	0.6	0.4	2105	28	12
moa	0.12	0.1	7439	43	3

Keyword	CPC	PCC	Volume	Score
methotrexate moa	0.17	0.6	4702	25
methotrexate moa in covid	0.73	0.4	8673	41
methotrexate moa in lupus	1.39	0.2	8755	30
methotrexate moa in psoriasis	1.18	0.3	7236	50
methotrexate moa in dermatology	1.82	0.7	1445	49
methotrexate moa in crohn's disease	1.58	0.9	8699	5
methotrexate moa in cancer	1.1	1	9955	43
methotrexate moa in ra	0.45	0.9	9609	11
methotrexate moa rheumatoid arthritis	0.94	0.1	9214	65
methotrexate moa in ectopic pregnancy	0.92	0.7	1286	58
methotrexate moa biochemistry	1.22	0.3	7761	63
taking methotrexate with covid	0.48	0.6	3007	91

Search Results related to methotrexate moa on Search Engine

Methotrexate - StatPearls - NCBI Bookshelf
nih.gov

https://www.ncbi.nlm.nih.gov/books/NBK556114/

WEBAug 16, 2023 · Methotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. This activity describes the indications, action, and contraindications for Methotrexate as a valuable agent in treating a wide variety of neoplastic diseases.

DA: 20 PA: 18 MOZ Rank: 23

Methotrexate: Uses, Interactions, Mechanism of Action
drugbank.com

https://go.drugbank.com/drugs/DB00563

WEBSep 21, 2014 · Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. 1 This inhibition leads to suppression of inflammation as well as prevention of cell division. 1 Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases ...

DA: 80 PA: 66 MOZ Rank: 81

Methotrexate - Wikipedia
wikipedia.org

https://en.m.wikipedia.org/wiki/Methotrexate

WEBMethotrexate ( MTX ), formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant. [4] . It is used to treat cancer, autoimmune diseases, and ectopic pregnancies. [4] . Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, gestational trophoblastic disease, and osteosarcoma. [4] .

DA: 53 PA: 52 MOZ Rank: 38

Methotrexate and its mechanisms of action in inflammatory ... - Nature
nature.com

https://www.nature.com/articles/s41584-020-0373-9

WEBFeb 17, 2020 · Methotrexate increases the expression of long intergenic non-coding RNA p21 (lincRNA-p21), which is a multifunction long non-coding RNA that regulates, both directly and indirectly, a variety of...

DA: 77 PA: 88 MOZ Rank: 39

Mechanism of action of methotrexate in rheumatoid arthritis
nature.com

https://www.nature.com/articles/nrrheum.2016.175

WEBOct 27, 2016 · 259 Citations. 44 Altmetric. Metrics. Key Points. Methotrexate shows good efficacy in a proportion of patients: 40% of treated patients with rheumatoid arthritis achieve an ACR50 response. The...

DA: 51 PA: 44 MOZ Rank: 26

Methotrexate and its mechanisms of action in inflammatory
nature.com

https://www.nature.com/articles/s41584-020-0373-9.pdf

WEBFeb 17, 2020 · Key points. methotrexate polyglutamates inhibit aminoimidazole-4-carboxamide ribonucleotide (aIcar) transformylase (aTIc), leading to intracellular accumulation of aIcar and increased...

DA: 71 PA: 27 MOZ Rank: 52

Methotrexate and its mechanisms of action in inflammatory arthritis
nih.gov

https://pubmed.ncbi.nlm.nih.gov/32066940/

WEBMethotrexate is generally the first-line drug for the treatment of RA, psoriatic arthritis and other forms of inflammatory arthritis, and it enhances the effect of most biologic agents in RA.

DA: 42 PA: 4 MOZ Rank: 7

Methotrexate: Dosage, Mechanism/Onset of Action, Half-Life
medicine.com

https://www.medicine.com/drug/methotrexate/hcp

WEBFeb 17, 2020 · Generic name: methotrexate systemic. Brand names: Trexall, Folex PFS, Rheumatrex Dose Pack, Methotrexate LPF Sodium, Otrexup, Rasuvo, Xatmep, RediTrex. Reviewed by Medicine.com on February 17, 2020. Boxed Warning. Dosage Forms. Pharmacology. Pharmacokinetics. Specific Populations. Use: …

DA: 28 PA: 48 MOZ Rank: 60

Molecular mechanism of action and pharmacokinetic properties
springer.com

https://link.springer.com/article/10.1007/s11033-020-05481-9

WEBMay 15, 2020 · Polyglutamation of methotrexate affects its pharmacokinetic and pharmacodynamic properties and prolongs its effect. Bile excretion plays significant role due to extensive enterohepatic recirculation, although majority of methotrexate is …

DA: 68 PA: 59 MOZ Rank: 82

Understanding the mechanisms of action of methotrexate ... - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/17922664/

WEBPMID: 17922664. Abstract. Methotrexate has been widely used for the treatment of rheumatoid arthritis (RA). The mechanisms of action of methotrexate are complex. Developed as a folic acid analogue, methotrexate inhibits purine and pyrimidine synthesis, which accounts for its efficacy in the therapy of cancer as well as for some of its toxicities.

DA: 73 PA: 12 MOZ Rank: 34