Keyword Analysis & Research: lcat


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lcat1.520.82443964

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  • LCAT deficiency: a systematic review with the clinical and …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276382/

    WebJul 13, 2021 · LCAT (lecithin-cholesterol acyltransferase) deficiency is characterized by two distinct phenotypes, familial LCAT deficiency (FLD) and Fish Eye disease (FED). This is the first systematic review evaluating the ethnic distribution of LCAT deficiency, with particular emphasis on Latin America and the discussion of three Mexican-Mestizo probands.

    DA: 4 PA: 26 MOZ Rank: 65

  • Lecithin–cholesterol acyltransferase - Wikipedia

    wikipedia.org

    https://en.wikipedia.org/wiki/Lecithin%E2%80%93cholesterol_acyltransferase

    WebLecithin–cholesterol acyltransferase ( LCAT, also called phosphatidylcholine–sterol O-acyltransferase) is an enzyme, in many animals including humans, that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, eventually making the newly synth...

    DA: 76 PA: 82 MOZ Rank: 53

  • Lecithin Cholesterol Acyltransferase Deficiency Disorders - Penn …

    pennmedicine.org

    https://www.pennmedicine.org/research-at-penn/online-research-interviews/understanding-lecithin-cholesterol-acyltransferase-deficiency-disorders

    WebDec 13, 2023 · Lecithin cholesterol acyltransferase (LCAT) deficiency is a genetic disorder that affects the body’s ability to process cholesterol. It is characterized by cloudiness of the clear front surface of the eye (corneal opacities), a shortage of red blood cells (hemolytic anemia), and kidney failure.

    DA: 33 PA: 87 MOZ Rank: 81

  • Lecithin Cholesterol Acyltransferase: An Anti- or Pro-atherogenic

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794709/

    WebLecithin cholesterol acyltransferase (LCAT) (EC2.3.1.43), a lipoprotein-associated enzyme, is a key player in the reverse cholesterol transport (RCT) pathway, which promotes the transfer of excess cellular cholesterol from peripheral tissues to the liver for excretion [ 1 ].

    DA: 83 PA: 11 MOZ Rank: 37

  • Lecithin cholesterol acyltransferase deficiency - Wikipedia

    wikipedia.org

    https://en.wikipedia.org/wiki/Lecithin_cholesterol_acyltransferase_deficiency

    WebPathophysiology. A deficiency of LCAT causes accumulation of unesterified cholesterol in certain body tissues. Cholesterol effluxes from cells as free cholesterol and is transported in HDL as esterified cholesterol. LCAT is the enzyme that esterifies the free cholesterol on HDL to cholesterol ester and allows the maturation of HDL.

    DA: 99 PA: 32 MOZ Rank: 51

  • LCAT- targeted therapies: Progress, failures and future

    sciencedirect.com

    https://www.sciencedirect.com/science/article/pii/S0753332222000658

    WebMar 1, 2022 · Lecithin: cholesterol acyltransferase (LCAT) is the only enzyme in plasma which is able to esterify cholesterol and boost cholesterol esterify with phospholipid-derived acyl chains.

    DA: 32 PA: 77 MOZ Rank: 13

  • Lecithin:Cholesterol Acyltransferase: From Biochemistry to Role …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910390/

    WebPurpose of review. We discuss the latest findings on the biochemistry of lecithin:cholesterol acyltransferase (LCAT), the effect of LCAT on atherosclerosis, clinical features of LCAT deficiency, and the impact of LCAT on cardiovascular …

    DA: 92 PA: 76 MOZ Rank: 80

  • Lecithin-Cholesterol Acyltransferase - an overview

    sciencedirect.com

    https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/lecithin-cholesterol-acyltransferase

    WebLecithin cholesterol acyltransferase (LCAT) is a glycoprotein that has both a phospholipase A2 and an acyltransferase action. It is essential for the normal maturation, interconversion and rearrangements of all lipoprotein classes and is involved in reverse cholesterol transport.

    DA: 41 PA: 10 MOZ Rank: 44

  • LCAT gene: MedlinePlus Genetics

    medlineplus.gov

    https://medlineplus.gov/genetics/gene/lcat/

    WebThe LCAT gene provides instructions for making an enzyme called lecithin-cholesterol acyltransferase (LCAT). Learn about this gene and related health conditions.

    DA: 39 PA: 71 MOZ Rank: 58

  • Find a Clinician : LearnYourLipids

    learnyourlipids.com

    https://www.learnyourlipids.com/find-a-clinician/

    WebA Diplomate of the American Board of Clinical Lipidology is a certified physician specializing in the prevention of dyslipidemia (cholesterol and other lipid disorders disorders) or related metabolic diseases (such as diabetes) which often lead to heart disease, stroke or atherosclerosis (vascular disease).

    DA: 64 PA: 75 MOZ Rank: 99