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What are some examples of gene mutation?

Gene mutation examples include severe genetic disorders, cell overgrowth, tumor formation and heightened risk of breast cancer. Cells have a finely tuned mechanism for correcting mutations at checkpoints during cell division, which detects most mutations. Once DNA proofreading is completed, the cell proceeds to the next stage of the cell cycle.

What are the causes of gene mutation?

A mutation is a change in the DNA sequence of an organism. Mutations can result from errors in DNA replication during cell division, exposure to mutagens or a viral infection. Germline mutations (that occur in eggs and sperm) can be passed on to offspring, while somatic mutations (that occur in body cells) are not passed on.

What is the definition of a genetic mutation?

Gene mutation is when any change occurs in the protein-coding sequence (in a gene) which ultimately affects the function governed by that specific protein, known as gene mutation. Point mutation– Point mutation occurs at a specific point in a sequence which is usually a single base change, often known as single nucleotide polymorphism.

What are the effects of gene mutations?

Gene mutations although cause minute change in the base pairing, its impact is largely felt by the organisms bearing such mutant gene. Generally mutations are harmful or deleterious and do not produce visible effects. Less than 20% mutations are lethal. The mutant genes when present in homozygous condition cause death of the organism.

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