Keyword Analysis & Research: epiplakin


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What is the function of Epiplakin?

"Epiplakin modifies the motility of the HeLa cells and accumulates at the outer surfaces of 3-D cell clusters." Cited for: FUNCTION, SUBCELLULAR LOCATION. "Effects of epiplakin-knockdown in cultured corneal epithelial cells." Cited for: FUNCTION.

What is the molecular mass of Epiplakin (epk1)?

Using the patient serum, they obtained a cDNA clone for the antigenic protein, which they called epiplakin, from a human keratinocyte expression library. They obtained full-length EPPK1 cDNA from HeLa cell and genomic cDNA libraries. The deduced protein contains 5,065 amino acids and has a calculated molecular mass of more than 552 kD.

What does EPPK1 stand for?

"Structure and heterogeneity of the human gene for epiplakin (EPPK1)." J. Invest. Dermatol. 121:1224-1226 (2003) [ PubMed] [ Europe PMC] [ Abstract]

How many amino acids are in EPPK1?

They obtained full-length EPPK1 cDNA from HeLa cell and genomic cDNA libraries. The deduced protein contains 5,065 amino acids and has a calculated molecular mass of more than 552 kD. Epiplakin has 13 domains that are homologous to the C-terminal B domain of desmoplakin (125647).


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