Understanding rare and common diseases in the context of …
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1093-y
WebNov 7, 2016 · Demography and purifying selection affect the purge of rare, deleterious mutations from the human population, whereas positive and balancing selection can increase the frequency of advantageous variants, improving survival and reproduction in specific environmental conditions.
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