cpt1a | Carnitine palmitoyltransferase I

Keyword	CPC	PCC	Volume	Score	Length of keyword
cpt1a	0.27	0.9	6931	96	5

Keyword	CPC	PCC	Volume	Score
cpt1a	0.93	0.7	5426	73
cpt1a gene	0.73	0.6	5203	29
cpt1a deficiency	0.04	0.6	8553	24
cpt1a antibody	0.47	1	1124	88
cpt1a cpt1b	0.15	0.6	8847	10
cpt1a arctic variant	1.5	0.6	63	34
cpt1a genecards	0.04	0.5	9907	54
cpt1a genereviews	0.71	0.6	6328	32

Search Results related to cpt1a on Search Engine

Carnitine palmitoyltransferase I - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Carnitine_palmitoyltransferase_I

WebThree isoforms of CPT1 are currently known: CPT1A, CPT1B, and CPT1C. CPT1 is associated with the outer mitochondrial membrane. This enzyme can be inhibited by malonyl CoA, the first committed intermediate produced during fatty acid synthesis.

DA: 23 PA: 66 MOZ Rank: 90

Carnitine Palmitoyltransferase 1A Deficiency - GeneReviews®
nih.gov

https://www.ncbi.nlm.nih.gov/books/NBK1527/

WebJul 27, 2005 · Carnitine palmitoyltransferase 1A (CPT1A) deficiency is a disorder of long-chain fatty acid oxidation. Clinical manifestations usually occur in an individual with a concurrent febrile or gastrointestinal illness when energy demands are increased; onset of symptoms is usually rapid.

DA: 92 PA: 47 MOZ Rank: 43

CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic ... - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/31900483/

WebFeb 1, 2020 · The CPT1 family of proteins contains 3 isoforms: CPT1A, CPT1B, and CPT1C. This review focuses on CPT1A, the liver isoform that catalyzes the rate-limiting step of converting acyl-coenzyme As into acyl-carnitines, which can then cross membranes to get into the mitochondria.

DA: 42 PA: 27 MOZ Rank: 83

CPT1A gene: MedlinePlus Genetics
medlineplus.gov

https://medlineplus.gov/genetics/gene/cpt1a/

WebThe CPT1A gene provides instructions for making an enzyme called carnitine palmitoyltransferase 1A, which is found in the liver. This enzyme is essential for fatty acid oxidation, a multistep process that breaks down (metabolizes) fats and converts them into energy. Fatty acid oxidation takes place within mitochondria, which are the energy ...

DA: 84 PA: 63 MOZ Rank: 42

CPT1A Gene - GeneCards | CPT1A Protein | CPT1A Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=CPT1A

WebApr 2, 2024 · Complete information for CPT1A gene (Protein Coding), Carnitine Palmitoyltransferase 1A, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium.

DA: 65 PA: 11 MOZ Rank: 8

CPT1A-mediated fatty acid oxidation promotes cell ... - Nature
nature.com

https://www.nature.com/articles/s41419-022-04730-y

WebApr 11, 2022 · 29 Citations. 1 Altmetric. Metrics. Abstract. As the first rate-limiting enzyme in fatty acid oxidation (FAO), CPT1 plays a significant role in metabolic adaptation in cancer pathogenesis. FAO...

DA: 84 PA: 95 MOZ Rank: 72

Upregulation of CPT1A is essential for the tumor-promoting
nature.com

https://www.nature.com/articles/s41419-020-02936-6

WebSep 10, 2020 · Here we demonstrate that carnitine palmitoyltransferase I (CPT1A), a key enzyme controlling fatty acid oxidation (FAO), was upregulated in colon cancer cells upon exposure to adipocytes or...

DA: 94 PA: 10 MOZ Rank: 27

CPT1A plays a key role in the development and treatment of
nature.com

https://www.nature.com/articles/s41598-019-49868-6

WebSep 16, 2019 · Human mutations in carnitine palmitoyl transferase 1A ( CPT1A) are correlated with a remarkably low prevalence of multiple sclerosis (MS) in Inuits (P479L) and Hutterites (G710E). To elucidate...

DA: 55 PA: 39 MOZ Rank: 3

Mitochondrial CPT1A: Insights into structure, function, and
nih.gov

https://pubmed.ncbi.nlm.nih.gov/37033619/

WebMar 23, 2023 · Abstract. Carnitine Palmitoyl-Transferase1A (CPT1A) is the rate-limiting enzyme in the fatty acid β-oxidation, and its deficiency or abnormal regulation can result in diseases like metabolic disorders and various cancers. Therefore, CPT1A is a desirable drug target for clinical therapy.

DA: 90 PA: 98 MOZ Rank: 82

CPT1A carnitine palmitoyltransferase 1A [ (human)]
nih.gov

https://www.ncbi.nlm.nih.gov/gene/1374

WebApr 7, 2024 · CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis. Augmented CPT1A Expression Is Associated with Proliferation and Colony Formation during Barrett's Tumorigenesis. The role of CPT1A as a biomarker of breast cancer progression: a bioinformatic approach.

DA: 37 PA: 16 MOZ Rank: 34