Activation of AMPKα1 is essential for regulatory T cell function …
https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC8632917/
WEBNov 2, 2021 · However, cotransfer of WT Treg cells, but not AMPKα1-deficient Treg cells, effectively suppressed weight loss and enlargement of the spleen and mesenteric lymph nodes (Fig. 5C, D). Consistent with these findings, histological analysis of Rag1 −/− mice that received WT Treg cells showed a lower degree of colon inflammation than mice that ...
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