Keyword Analysis & Research: clazakizumab side effects


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Frequently Asked Questions

What is clazakizumab used to treat?

Clazakizumab, a humanized anti–IL-6 mAb, is used in the phase II clinical trial for the treatment of RA patients [89 ]. It has also been evaluated for the treatment of non-small cell lung cancer (NSCLC) and patients with head and neck cancer [ 90 ].

What are the side effects of Crizanlizumab?

Some side effects may occur within 24 hours after you receive crizanlizumab. Tell your caregiver if you feel dizzy, nauseated, tired, itchy, chilled, sweaty, or have a fever, wheezing, or shortness of breath. Tell your doctor if you are pregnant or breastfeeding.

How is clazakizumab different from other IL-6 agonists?

By virtue of engineered aglycosylation, clazakizumab has a longer half-life than other mAb reagents targeting IL-6 or IL-6R, thereby requiring less frequent dosing; however, with higher dose ranges, the frequency of serious adverse events and infections appears to be increased.

Can a 16 year old take Crizanlizumab?

Crizanlizumab is for use in adults and children at least 16 years old. Crizanlizumab may also be used for purposes not listed in this medication guide. Some side effects may occur within 24 hours after you receive crizanlizumab.


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