celastrol | Celastrol

Keyword	CPC	PCC	Volume	Score	Length of keyword
celastrol	1.04	0.1	6282	86	9

Keyword	CPC	PCC	Volume	Score
celastrol	0.94	0.8	9196	24
celastrol supplement	1.81	0.5	9526	18
celastrol paraptosis	1.86	0.2	6741	8
celastrol tablets	1.77	0.6	8316	9
celastrol treatment	0.92	0.8	996	9
celastrol leptin	0.46	0.2	9768	91
cholesterol normal range	0.94	0.6	15	100
celastrol side effects	0.68	0.2	7552	78
celastrol solubility	1.76	0.8	9246	27
celastrol obesity	1.73	0.3	8924	100
celastrol side effects in hindi	0.6	0.3	7170	17

Search Results related to celastrol on Search Engine

Celastrol - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Celastrol

WebCelastrol is a pentacyclic nortriterpen quinone and belongs to the family of quinone methides. In mice, celastrol is an NR4A1 agonist that alleviates inflammation and induces autophagy. Also in mice, celastrol increase expression of IL1R1, which is the receptor for the cytokine interleukin-1 (IL-1). IL1R1 knock-out mice exposed to celastrol ...

DA: 21 PA: 41 MOZ Rank: 83

Biosynthesis and biotechnological production of the anti ... - Nature
nature.com

https://www.nature.com/articles/s41557-023-01245-7

WebJun 26, 2023 · Celastrol is a potent anti-obesity agent found in the root of Tripterygium wilfordii, but its medicinal application is compromised by limited availability. Now, by combining plant biochemistry...

DA: 33 PA: 30 MOZ Rank: 29

Frontiers | Celastrol: A Review of Useful Strategies Overcoming …
frontiersin.org

https://www.frontiersin.org/articles/10.3389/fphar.2020.558741/full

WebNov 18, 2020 · Celastrol, a natural bioactive ingredient derived from Tripterygium wilfordii Hook F, exhibits significant broad-spectrum anticancer activities for the treatment of a variety of cancers including liver cancer, breast cancer, prostate tumor, …

DA: 34 PA: 64 MOZ Rank: 32

Celastrol | C29H38O4 | CID 122724 - PubChem
nih.gov

https://pubchem.ncbi.nlm.nih.gov/compound/celastrol

WebCelastrol is a pentacyclic triterpenoid that is 24,25,26-trinoroleana-1 (10),3,5,7-tetraen-29-oic acid bearing an oxo substituent at position 2, a hydroxy substituent at position 3 and two methyl groups at positions 9 and 13. An antioxidant and anti-inflammatory agent.

DA: 46 PA: 32 MOZ Rank: 58

Celastrol suppresses colorectal cancer via covalent targeting
nature.com

https://www.nature.com/articles/s41392-022-01231-4

WebFeb 3, 2023 · Celastrol is one of the most promising medicinal natural products isolated from traditional medicines. 1 As a pentacyclic triterpene (Fig. 1a) isolated from the plant Thunder God Vine,...

DA: 33 PA: 47 MOZ Rank: 45

Celastrol and its Role in Chronic Diseases - PMC - National …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056454/

WebCelastrol, a natural triterpene, has anti-inflammatory, anti-oxidant, and anti-cancer activities. Besides targeting multiple cell signaling pathways, celastrol modulates several other pathophysiological processes involved in chronic inflammatory diseases, autoimmune diseases, and cancer.

DA: 39 PA: 76 MOZ Rank: 85

Celastrol: A Promising Agent Fighting against Cardiovascular …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405053/

WebAug 18, 2022 · Celastrol, a bioactive compound isolated from the roots of the plant Tripterygium wilfordii (TW), has been attracting increasing research attention in recent years, as it exerts cardiovascular treatment benefits targeting both CVD and their associated risk factors. Substantial evidence has revealed a protective role of celastrol against a broad ...

DA: 91 PA: 35 MOZ Rank: 19

Celastrol - an overview | ScienceDirect Topics
sciencedirect.com

https://www.sciencedirect.com/topics/medicine-and-dentistry/celastrol

WebCelastrol (Fig. 8) is a natural product derived from the Celastraceae family of plants ( Kutney et al., 1981 ). Extracts containing celastrol have been used for the treatment of fever, joint pain, and edema without evidence of carcinogenicity or other limiting side effects ( Allison et al., 2001 ).

DA: 96 PA: 94 MOZ Rank: 47

Celastrol: A Review of Useful Strategies Overcoming its …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/33364939/

WebNov 18, 2020 · Celastrol, a natural bioactive ingredient derived from Tripterygium wilfordii Hook F, exhibits significant broad-spectrum anticancer activities for the treatment of a variety of cancers including liver cancer, breast cancer, prostate tumor, multiple myeloma, glioma, etc. However, the poor wat …

DA: 98 PA: 68 MOZ Rank: 33

Celastrol as an emerging anticancer agent: Current status
nih.gov

https://pubmed.ncbi.nlm.nih.gov/37196541/

WebCelastrol is a pentacyclic triterpenoid extracted from the traditional Chinese medicine Tripterygium wilfordii Hook F., which has multiple pharmacological activities. In particular, modern pharmacological studies have demonstrated that celastrol exhibits significant broad-spectrum anticancer activit …

DA: 86 PA: 62 MOZ Rank: 44