Intravenous Bolus and Infusion | SpringerLink
https://link.springer.com/referenceworkentry/10.1007/978-3-030-84860-6_97
WEBJan 1, 2022 · If a faster onset of the therapeutic action is required, it is a common practice to combine an IV bolus with the infusion. The bolus, administered at the beginning of the infusion, is called a loading dose (D L). The longer the half-life of the drug, the longer the time required to reach the steady state and, therefore, the more justified the ...
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